 epidemiology and genomics of a slow outbreak of methicillin resistant staphyloccus aureus mrsa in a neonatal intensive care unit successful chronic decolonization of mrsa positive healthcare personnel a nicu experienced aslow and sustained mrsa outbreak involving 15 babies and 6 healthcare personnel multiple progressive infection prevention interventions were implemented including contact precautions and cohorting of mrsa positive babies hand hygiene observers enhanced environmental cleaning screening of babies and staff and decolonization of carriers identifying and decolonizing persistent mrsa carriage among staff was successful in stopping transmission and ending the outbreak 