 outbreak of ndm 1 and oxa 181 producing klebsiella pneumoniae bloodstream infections in a neonatal unit south africa following an increase in carbapenem resistant klebsiella pneumoniae crkp bloodstream infections and associated deaths in the neonatal unit of a south african hospital an outbreak investigation was conducted october 2019 february 2020 and cross sectional follow up march 2020 may 2021 genomic and epidemiologic data was used to reconstruct transmission networks of outbreak related clones which allowed for identified 31 cases of culture confirmed crkp infection 14 deaths and two outbreak related clones 